Oral integrin therapies for patients with immunological, fibrotic, neoplastic and vascular diseases.
Morphic Tx is joining a three decade quest led by our scientific founder, Tim Springer, who initially discovered the integrin receptor family in the 1980s. This receptor family is an important drug target that has fueled the successful development of six injectable therapies approved for treatment of multiple sclerosis, ulcerative colitis, Crohn's disease, plaque psoriasis, acute coronary syndrome and complications during percutaneous coronary intervention.
Despite blockbuster commercial success, integrins have remained out of reach as small molecule drugs...until now.