Brian Gastman Email

EVP Medical Affairs . Iovance Biotherapeutics

Current Roles

Employees:
550
Revenue:
$13.8M
About
Iovance Biotherapeutics is focused on the development and commercialization of novel cancer immunotherapies based on tumor infiltrating lymphocytes (TIL). This approach, also known as adoptive T-cell therapy, was initially developed by Dr. Steven A. Rosenberg at the National Cancer Institute (NCI). In Phase 2 clinical trials conducted at the NCI, 56% and 24% of patients treated with this technology were reported by NCI to have achieved objective and complete response criteria, respectively. Our lead product candidate is an autologous, ready-to-infuse cell therapy, that has demonstrated distinctive efficacy in the treatment of metastatic melanoma. In addition to metastatic melanoma, carcinoma of the head and neck and cervical cancer our TIL therapy technology is potentially applicable to many other tumor types, including ovarian, breast, bladder, colorectal and other cancers. As we continue advancing our current clinical programs through the introduction of manufacturing and logistical efficiencies aimed at decreasing production time and optimizing distribution processes, we aim to establish TIL therapy as a revolutionary, accessible, mainline cancer therapy.
Iovance Biotherapeutics Address
999 Skyway Road
San Carlos, CA
United States
Iovance Biotherapeutics Email

Past Companies

Iovance Biotherapeutics, Inc.Executive Vice President of Medical Affairs
Cleveland ClinicAdjunct Professor of Surgery
Cleveland ClinicSurgical and Co-Director of the Cleveland Clinic Melanoma Program

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