The Prince Edward Island BioAlliance is the private sector-led not-for-profit organization that is responsible for developing and coordinating the strategy for the growth of the Prince Edward Island Bioscience Cluster. Since 2005, the BioAlliance has facilitated the work of businesses, academic and research institutions, and federal and provincial government agencies in establishing the bioscience sector as a key pillar in the economic foundation of the province and Atlantic Canada. Building from plans developed since 2005, the collaborative model of the BioAlliance has enabled a unique shared vision, an alignment on priorities and strategy, and allocation of resources, that has delivered results. This collaboration has been the driving force of the bio-economy growth to date, and has achieved the PEI Bioscience Cluster recognition as an important element of Canada’s innovation ecosystem.