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Nathanael Dolesh Email
Software & Hardware Integration Engineer . Cell X Technologies
Cleveland, OH
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We develop and provide equipment, software, and processes that support stem cell research and bio-fabrication. Using quantitative large field of view image analysis and automation for the reproducible analysis and selection of cells and cell populations. These tools and services enable the development of safe and effective cell and gene therapy, cell manufacturing, cell-based drug testing, and disease modeling. Successful cellular therapies demand starting with optimized cell sources. Intrinsic variability and heterogeneity among available cell sources in biological system presents a major challenge in the use of cells for clinical or diagnostic purposes. This critical first step of control over starting materials demands the development and use of quantitative and reproducible standards for cell and clone selection and process management based on critical process parameters (CPPs), to achieve and end product with defined critical quality attributes (CQAs) that predict clinical and operational performance. . The Cell X Platform is a robust and versatile system that enables process management using precisely defined protocol for imaging and cell/clone selection. We have particular experience with connective tissue progenitor cells (CTPs), mesenchymal stromal (“stemâ€) cells (MSCs), and induced pluripotent stem cells (iPS). The integration of imaging and process management and documentation enables you as a user to “See what you have - Pick what you want - Show what you’ve done - and Know how to do it again.†We are committed to work with you to apply these systems to your problems. In doing so, we seek to contribute to the ongoing transformation of stem and progenitor cell biology into safe, effective and affordable diagnostic and therapeutic procedures that improve all of our lives. Please contact us about becoming a Beta user of the Cell X platform.Cell X Technologies Address
10000 Cedar AveCleveland, OH