The City of Lathrop is a small city with a BIG presence. The City of Lathrop is located 70± miles east of San Francisco and 55± miles south of Sacramento within the Northern San Joaquin Valley Mega-region. Joined at the convergence of Interstate 5, Interstate 205 and State Route Highway 120, the City of Lathrop is truly at the "crossroads of commerce." To learn more about the City of Lathrop, please visit our website at www.ci.lathrop.ca.us or contact us at EconDev@ci.lathrop.ca.us.