InSitu Biologics, LLC is an emerging biotech company focusing on development of new and proprietary treatments using its Matrixâ„¢ BioHydrogel. Their lead product, AnestaGelâ„¢, is a long-lasting and long-acting non-opiate painkiller, targeted for use in peri-operative regional pain management. AnestaGelâ„¢ uses a novel approach to delivering sustained-released analgesics into the target tissue via the Matrixâ„¢ BioHydrogel platform, which is a tunable, biocompatible, and pH neutral platform. This allows AnestaGelâ„¢ to provide target site-specific, non-migratory placement, a flexible and high dose drug-load reservoir capacity, and a tunable and predictable pharmacological effect.