As a CDMO our focus is to combine technical leadership in cell culture, microbial fermentation and viral vectors with world class cGMP manufacturing facilities to advance tomorrow's medicines. For over 25 years our focus has been on supporting our customers with the development and manufacture of recombinant proteins, viral vaccines and gene therapies.
Our Competencies and Capabilities:
Expertise with products expressed in a wide range of expression platforms including: microbial fermentation (e.g., E. coli, P. pastoris), cell culture systems including CHO , HEK, Vero, MDCK, EB66 and insect cells, and transgenics.
Extensive viral vector experience, including the process development, scale up and cGMP production of: Adenovirus, Adeno-associated virus (AAV), Lentivirus, Poxvirus and Baculovirus among others.
In-house developed Microbial (pAVEway) and mammalian (Apollo) expression platforms
Cell banking capabilities
Full life-cycle biological and viral products manufacturing from initial concept to commercial product
Analytical and Formulation Development Services for biologics, vaccines and advanced therapies
Expertise in Process Characterization Studies with over 44 programs completed
Our cGMP Manufacturing Capabilities
Cell Culture cGMP Manufacturing Capabilities ranging from 100L to multiple 2,000L
Microbial Fermentation Manufacturing cGMP Capabilities ranging from 100L to multiple 5,000L.
20,000L large scale microbial production in collaboration with MSD
Low dose biologics cGMP Manufacturing capabilities
Gene Therapy and viral vector cGMP manufacturing facilities supporting production from pre-clinical to commercial production