NxStage Medical, Inc. was founded in 1998 to develop and market novel technologies for the treatment of kidney failure. The NxStage System One is a breakthrough design that delivers hemodialysis, hemofiltration, and/or ultrafiltration to patients with renal failure or fluid overload. The system is compact and portable; it requires only a standard electrical outlet and no water processing. Its user-friendly interface and drop-in, disposable cartridge are designed for ease-of-use and streamlined training.