Brad Gliner Email

VP, Clinical Research and Regulatory Affairs . Arcellx

Gaithersburg, MD

Location

b******@arcellx.com

Primary Email

Current Roles

Employees:
172
Revenue:
$33.3M
About
Arcellx is a clinical-stage biopharmaceutical company developing novel, adaptive and controllable cell therapies for the treatment of patients with cancer and autoimmune diseases. The Company's proprietary ARC-sparX platform separates the tumor-recognition and tumor-killing functions of conventional CAR-T cell therapies: (1) sparX (soluble protein antigen-receptor X-linkers) proteins recognize and bind specific antigens on diseased cells and flag those cells for destruction; and (2) ARC-T (Antigen Receptor Complex-T) cells bind the sparX proteins and kill the flagged cells. Arcellx has developed a collection of sparX proteins that bind different cell surface antigens. Administration of alternate sparX proteins can redirect ARC-T cells to different disease antigens to potentially address relapsed and refractory disease due to tumor heterogeneity or antigen escape. Additionally, ARC-T cell activity can be curbed as needed by controlling the dose and frequency of sparX administration.
Arcellx Address
25 W. Watkins Mill Road
Gaithersburg, MD
United States
Arcellx Email

Past Companies

Arcellx, Inc.Vice President, Clinical Research and Regulatory Affairs
IndependentClinical and Regulatory Consultant
Nevro CorpVice President of Clinical and Regulatory Affairs

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