Hesperos Revenue and Competitors

Hesperos, Inc, is a leader in efforts to characterize an individual’s biology with human-on-a-chip microfluidic systems. Founders Michael L. Shuler and James J. Hickman have been at the forefront of every major scientific discovery in this realm, from individual organ-on-a-chip constructs to fully functional, interconnected multi-organ systems which they coined "human-on-a-chip". With a mission to revolutionize toxicology testing as well as efficacy evaluation for drug discovery, the company has created pumpless platforms with serum-free cellular mediums that allow multi-organ system communication and integrated computational modeling of live physiological responses of functional neurons, cardiac, muscle, and neuromuscular junctions as well as liver, pancreas and barrier tissues. Created from human stem cells, the fully human systems are the first in vitro solutions that accurately recreate in vivo functions without the use of animal models, as featured in Science. Unlike other tests that extrapolate organ function based on biomarker activity and protein analysis, our models are working systems that recreate muscle and tissue function, as well as neural and inter-organ communication. Functional reports generated by our models closely correlate to what clinicians observe in human clinical trials. Our tools also allow more accurate modeling of drug responses under realistic treatment conditions, including “chronic dosing” over extended periods of time.